Mercedes-Benz AMG E53 Hybrid 4matic Plus MPG by year — every rating on record
The Mercedes-Benz AMG E53 Hybrid 4matic Plus has a combined EPA fuel economy rating for 2 model years, from 2025 to 2026. Across those years its best rated version returned 24 mpg (2026) and its thirstiest returned 23 mpg (2025). The EPA record holds 2 configurations for this nameplate, most recently a Midsize Cars.
Year-by-year EPA ratings
| Model year | Configurations | Best combined | Worst combined | Class rank that year | Drivetrains | Fuel | EPA class |
|---|---|---|---|---|---|---|---|
| 2025 | 1 | 23 mpg | 23 mpg | #71 of 86 (18th pct) | All-Wheel Drive | Premium and Electricity | Midsize Cars |
| 2026 | 1 | 24 mpg | 24 mpg | #58 of 66 (12th pct) | All-Wheel Drive | Premium and Electricity | Midsize Cars |
Where it has stood in its class
Ranked against every other nameplate the EPA filed under the same class that year. The Mercedes-Benz AMG E53 Hybrid 4matic Plus placed highest in 2026 at #58 of 66, and lowest in 2025 at #71 of 86. It spent 0 of its 2 ranked years in the top half of its class.
Every configuration on record
All 2 configurations EPA lists for this nameplate, newest first.
| Year | Configuration | Engine detail | City | Highway | Combined | Gallons/yr | Barrels/yr | EPA fuel cost/yr | Range | CO2 g/mi | GHG |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 3.0L 6-cyl All-Wheel Drive Automatic 9-spd Premium and Electricity | SIDI; PHEV, turbocharged, Plug-in Hybrid | 22 | 27 | 24 | 479.2 | 3.8 | $3,250 | 420 mi | 115 | 9/10 |
| 2025 | 3.0L 6-cyl All-Wheel Drive Automatic 9-spd Premium and Electricity | SIDI; PHEV, turbocharged, Plug-in Hybrid | 21 | 26 | 23 | 500.0 | 4.0 | $3,350 | 410 mi | 117 | 9/10 |
How the rating has moved between model years
Comparing the best-rated configuration of each year. 1 of 1 year-over-year steps improved the top rating.
| Change | Best combined | Delta | Gallons a year at the newer rating |
|---|---|---|---|
| 2025 → 2026 | 23 → 24 mpg | +1 mpg | 479 gal |
What AMG E53 Hybrid 4matic Plus fuel costs over a year
At the EPA's 11,500 miles a year, the 2026 Mercedes-Benz AMG E53 Hybrid 4matic Plus burns 479 to 479 gallons depending on configuration. Below is what that costs at three pump prices, and how much more the thirstiest configuration costs than the most efficient one.
| Pump price | Most efficient | Thirstiest | Spread |
|---|---|---|---|
| $3.00/gal | $1,438 | $1,438 | $0 |
| $3.50/gal | $1,677 | $1,677 | $0 |
| $4.00/gal | $1,917 | $1,917 | $0 |
EPA’s own estimate for the 2026 model year is $3,250 to $3,250 a year in fuel, or $2,000 less than the average new vehicle over five years.
How it compares with other Midsize Cars
Across the 483 nameplates EPA classifies as Midsize Cars, the median best combined rating is 25 mpg. At 24 mpg the Mercedes-Benz AMG E53 Hybrid 4matic Plus is 1 mpg below the median, which is worth about $67 a year at $3.50 a gallon.
- All Midsize Cars rankings — every nameplate in the class, best to worst.
Other Mercedes-Benz nameplates
Every Mercedes-Benz model compared → — all nameplates ranked by best combined rating, with what each one costs a year.