Mercedes-Benz GLS450 4matic MPG by year — every rating on record
The Mercedes-Benz GLS450 4matic has a combined EPA fuel economy rating for 10 model years, from 2017 to 2026. Across those years its best rated version returned 21 mpg (2020) and its thirstiest returned 18 mpg (2019). The EPA record holds 10 configurations for this nameplate, most recently a Standard Sport Utility Vehicle 4WD.
Year-by-year EPA ratings
| Model year | Configurations | Best combined | Worst combined | Class rank that year | Drivetrains | Fuel | EPA class |
|---|---|---|---|---|---|---|---|
| 2017 | 1 | 19 mpg | 19 mpg | #34 of 78 (57th pct) | 4-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2018 | 1 | 19 mpg | 19 mpg | #33 of 76 (57th pct) | 4-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2019 | 1 | 18 mpg | 18 mpg | #46 of 81 (44th pct) | 4-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2020 | 1 | 21 mpg | 21 mpg | #31 of 92 (67th pct) | 4-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2021 | 1 | 21 mpg | 21 mpg | #38 of 104 (64th pct) | 4-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2022 | 1 | 20 mpg | 20 mpg | #64 of 126 (50th pct) | 4-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2023 | 1 | 20 mpg | 20 mpg | #73 of 139 (48th pct) | All-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2024 | 1 | 21 mpg | 21 mpg | #91 of 166 (45th pct) | All-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2025 | 1 | 21 mpg | 21 mpg | #117 of 192 (39th pct) | All-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
| 2026 | 1 | 21 mpg | 21 mpg | #116 of 191 (39th pct) | All-Wheel Drive | Premium | Standard Sport Utility Vehicle 4WD |
Where it has stood in its class
Ranked against every other nameplate the EPA filed under the same class that year. The Mercedes-Benz GLS450 4matic placed highest in 2020 at #31 of 92, and lowest in 2025 at #117 of 192. It spent 4 of its 10 ranked years in the top half of its class.
Every configuration on record
All 10 configurations EPA lists for this nameplate, newest first.
| Year | Configuration | Engine detail | City | Highway | Combined | Gallons/yr | Barrels/yr | EPA fuel cost/yr | CO2 g/mi | GHG |
|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 3.0L 6-cyl All-Wheel Drive Automatic 9-spd Premium | SIDI; Mild Hybrid, supercharged, turbocharged, Hybrid, start-stop | 19 | 24 | 21 | 547.6 | 14.2 | $3,700 | 428 | 4/10 |
| 2025 | 3.0L 6-cyl All-Wheel Drive Automatic 9-spd Premium | SIDI; Mild Hybrid, supercharged, turbocharged, Hybrid, start-stop | 19 | 24 | 21 | 547.6 | 14.2 | $3,700 | 428 | 4/10 |
| 2024 | 3.0L 6-cyl All-Wheel Drive Automatic 9-spd Premium | SIDI; Mild Hybrid, turbocharged, Hybrid, start-stop | 19 | 24 | 21 | 547.6 | 14.2 | $3,700 | 428 | 4/10 |
| 2023 | 3.0L 6-cyl All-Wheel Drive Automatic 9-spd Premium | SIDI; Mild Hybrid, turbocharged, Hybrid, start-stop | 18 | 23 | 20 | 575.0 | 14.9 | $3,900 | 433 | 4/10 |
| 2022 | 3.0L 6-cyl 4-Wheel Drive Automatic 9-spd Premium | SIDI; Mild Hybrid, turbocharged, Hybrid, start-stop | 18 | 24 | 20 | 575.0 | 14.9 | $3,900 | 433 | 4/10 |
| 2021 | 3.0L 6-cyl 4-Wheel Drive Automatic 9-spd Premium | SIDI; Mild Hybrid, turbocharged, Hybrid, start-stop | 20 | 24 | 21 | 547.6 | 14.2 | $3,700 | 414 | 4/10 |
| 2020 | 3.0L 6-cyl 4-Wheel Drive Automatic 9-spd Premium | SIDI; Mild Hybrid, turbocharged, Hybrid, start-stop | 19 | 23 | 21 | 547.6 | 14.2 | $3,700 | 429 | 4/10 |
| 2019 | 3.0L 6-cyl 4-Wheel Drive Automatic 9-spd Premium | SIDI, turbocharged, start-stop | 16 | 22 | 18 | 638.9 | 16.5 | $4,300 | 488 | 3/10 |
| 2018 | 3.0L 6-cyl 4-Wheel Drive Automatic 9-spd Premium | SIDI, turbocharged, start-stop | 17 | 22 | 19 | 605.3 | 15.7 | $4,100 | 477 | 3/10 |
| 2017 | 3.0L 6-cyl 4-Wheel Drive Automatic 9-spd Premium | SIDI, turbocharged, start-stop | 17 | 22 | 19 | 605.3 | 15.7 | $4,100 | 477 | 4/10 |
How the rating has moved between model years
Comparing the best-rated configuration of each year. 2 of 4 year-over-year steps improved the top rating.
| Change | Best combined | Delta | Gallons a year at the newer rating |
|---|---|---|---|
| 2018 → 2019 | 19 → 18 mpg | -1 mpg | 639 gal |
| 2019 → 2020 | 18 → 21 mpg | +3 mpg | 548 gal |
| 2021 → 2022 | 21 → 20 mpg | -1 mpg | 575 gal |
| 2023 → 2024 | 20 → 21 mpg | +1 mpg | 548 gal |
What GLS450 4matic fuel costs over a year
At the EPA's 11,500 miles a year, the 2026 Mercedes-Benz GLS450 4matic burns 548 to 548 gallons depending on configuration. Below is what that costs at three pump prices, and how much more the thirstiest configuration costs than the most efficient one.
| Pump price | Most efficient | Thirstiest | Spread |
|---|---|---|---|
| $3.00/gal | $1,643 | $1,643 | $0 |
| $3.50/gal | $1,917 | $1,917 | $0 |
| $4.00/gal | $2,190 | $2,190 | $0 |
EPA’s own estimate for the 2026 model year is $3,700 to $3,700 a year in fuel, or $7,250 more than the average new vehicle over five years.
How it compares with other Standard Sport Utility Vehicle 4WD
Across the 317 nameplates EPA classifies as Standard Sport Utility Vehicle 4WD, the median best combined rating is 22 mpg. At 21 mpg the Mercedes-Benz GLS450 4matic is 1 mpg below the median, which is worth about $87 a year at $3.50 a gallon.
- All Standard Sport Utility Vehicle 4WD rankings — every nameplate in the class, best to worst.
Other Mercedes-Benz nameplates
Every Mercedes-Benz model compared → — all nameplates ranked by best combined rating, with what each one costs a year.